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Quick Details

  • CAS No.: 2124-57-4 (27670-94-6), 2124-57-4 (27670-94-6)
  • Other Names: Menaquinon-7; MK-7; Vitamin K2 MK7
  • MF: C46H64O2
  • EINECS No.: N/A
  • Place of Origin: Shaanxi, China (Mainland)
  • Type: Vitamins, Amino Acids and Coenzymes
  • Grade Standard: Medicine Grade
  • Brand Name: N&R
  • Model Number: MK-7
  • Purity: 0.2%~1.5%
  • Product Name: vitamin k2(35) /MK7
  • Appearance: Yellow crystals powder
  • Assay: 1.3%~98%
  • M.F.: C46H64O2
  • Test Method: HPLC
  • Package: 25Kg/Drum
  • Product Type: Pharmacetical
  • MOQ: 1Kg
  • Name: Factory supply top quality Vitamin k2 (35)/MK-7/Vitamin k2 mk7

Packaging & Delivery

Packaging Details 1 Kg/Aluminum foil bag ;25kg/Drum
Factory supply top quality Vitamin k2 (35)/MK-7/Vitamin k2 mk7
Delivery Time 3-5 days after receiving payment

ProductIntroduction                                                                                                                                    

Vitamin K2 or menaquinone  has nine related compounds, generally subdivided into the short-chain menaquinones (with MK-4 as the most important member) and the long-chain menaquinones, of which MK-7,  and MK-9 are nutritionally the most recognized.

 Vitamin K2(35)/ MK-7/Menatetrenone 7/ Menaquinon-7   (Fermentation)

 

Alternative Names: Menaquinon-7; MK-7; (all-E)-2-(3,7,11,15,19,23,27-Heptamethyl -2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione ;

CAS No.:  2124-57-4 (27670-94-6)                     

Molecular Formula:  C46H64O2

Molecular Weight:  649.0                             

Hazard Class:  Safe       

     

 

 

 

 

 Vitamin K2(20), MK-4 / Menatetrenone  (Synthetic)

 

Menatetrenone , also known as MK4, is a vitamin K compound used as a hemostatic agent, and also as adjunctive therapy for the pain of osteoporosis. Menatetrenone is one of the nine forms of vitamin K2.

 

Menatetrenone:Vitamin K2, menaquinone, menaquinon-4, menatetrenone, menatetren, menatetrenona, menatetrenonum, MK-4, E3100; 2-methyl-3-[(2'E,6'E,10'E)-3',7',11',15'- tetramethylhexadeca-2',6',10',14'- tetraen-1'-yl]-1,4-naphthalenedione

Molecular Structure:

Molecular Formula:C31H40O2

Molecular Weight:444.65

 

CAS Registry Number:863-61-6/11032-49-8

 

 

 

Product Analysis                                                                                                                                             

 

 

Vitamin K2 MK-7 1.3% powder

Items

Specification

Results

Appearance

Pale yellow or white crystalline powder

Pale yellow or white crystalline powder

Purity (HPLC,Menaquinone-7)

≥1.3%(>13000ug/g)

1.32%

Pharm.excipient  (Carbohydrate)

≥90.0%

90.7%

Identification

Yellow brown precipitate

Yellow brown precipitate

PH

5.5~8.0

6.5

Loss on drying

≤10.0%

7.9%

Residue on ignition

≤0.1%

<0.1%

Reducing sugar

≤0.2%

<0.2%

Starch

Negative

Negative

Fatty acid

Negative

Negative

Heavy metals

≤10ppm

<10ppm

Arsenic

≤2ppm

Complies

Pesticides residue

Negative

Negative

Total aerobic count (CFU/g)

≤1000

Complies

Yeasts & Molds (CFU/g)

≤100

Complies

Salmonella SP.

Negative

Negative

E. Coli

Negative

Negative

 

Vitamin K2 MK-4 1.3% powder


 Function & Appliction                                                                                                                                

Functions of Vitamin K2

1. Curing and preventing osteoporosis: VK2 produces a specific protein known as osteocalcin which can bind calcium, therefore to increase the density of bones and to prevent fracture.

 2. Curing haemorrhage caused by VK2 deficiency: It promotes the formation of thrombin, accelerates blood clotting, maintains proper clotting time; and also used as quick coagulant in surgeries or first aids.

 3. Function of diuresis, promoting the detoxifcation of liver and lowering blood pressure.

 4. VK2 is a PKA active regulator used for preventing and treating hepatic disease. And it can be used for treating liver cancer and lung cancer.  

 

Vitamin K2’s effects on osteoporosis

 Vitamin K2 is a cofactor of gamma-carboxylase, which converts the glutamic acid (Glu) residue in steocalcin molecules to gamma-carboxyglutamic acid (Gla), and is, therefore, essential for gamma-carboxylation of osteocalcin. Vitamin K2 also enhances osteocalcin accumulation in the extracellular matrix of osteoblasts in vitro. Osteocalcin-knockout mice develop hyperostosis, suggesting that the Gla-containing osteocalcin promotes normal bone mineralization, and it probably regulates the growth of hydroxyapatite crystals. Vitamin K2 also inhibits the expression of the osteoclast differentiation factor (ODF)/RANK ligand, tartrate-resistant acid phosphatase activity, and mononuclear cell formation, and induces osteoclast apoptosis in vitro.

 

Furthermore, bone pectin is formed by osteocalcin produced with vitamin K2 and protein, and calcium, then caccumulates in bone. So vitamin K2, calcium and protein are three factors which are essential to increase bone density. There is some evidence indicating that vitamin K2 prevents bone resorption in ovariectomized rats, retards the increase in bone turnover in orchidectomized rats, ameliorates the increase in bone resorption and decrease in bone formation in sciatic neurectomized rats, and prevents the decrease in bone formation in glucocorticoid-treated rats. These findings suggest that vitamin K2 may not only stimulate bone formation but also suppress bone resorption in vivo. Clinically, vitamin K2 sustains the lumbar bone mineral density (BMD) and prevents osteoporotic fractures in patients with age-related osteoporosis, prevents vertebral fractures in patients with glucocorticoid-induced osteoporosis, increases the metacarpal BMD in the paralytic upper extremities of patients with cerebrovascular disease, and sustains the lumbar BMD in patients with liver-dysfunction-induced osteoporosis.

 

 

Related  Vitamin K2 Product we supply  

 

 

 

Why choose US?

1. We has 8 years’ exporting experience in active pharmaceutical ingredient products.  Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with thousands of products of different levels.

3. We offer convenient one-station purchasing service.

 

4. After an order is placed, when to deliver? It depends on whether the products you buy has inventory. If we have inventory, generally we can 

arrange shipment after receipt of payment 2 to 3 days. If not, it will be decided by the time of the factory production.

 

Package & Shipping                                                                                                                                       

Packaging Details:  1 Kg/Aluminum foil bag ;25kg/Drum,or according to the customer's demand

Delivery Details  within 3 -7 days after receiving payments

Storage: Store in a cool, dry, well ventilated place out of direct sunlight.

Shipping details: DHL;TNT;FEDEX or EMS

 

 

 

 N&R INDUSTRIES,INC

Tel: +86-29-88764861   Fax: +86-29-88764861

Mobile: (Anne)+86-15934835307

http://www.nutraii.com/

http://nutraii.en.alibaba.com

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